Pharmaceuticals

GxP-Compliant LIMS for Pharmaceutical QC, QA, and Stability Testing

LIMSera streamlines pharmaceutical quality control and quality assurance workflows with validated electronic records, 21 CFR Part 11 compliant e-signatures, and end-to-end batch traceability. Manage raw material testing, in-process controls, finished product release, and ICH stability studies from a single platform. Automate out-of-specification (OOS) investigations, generate Certificates of Analysis (CoA), and maintain audit-ready documentation that satisfies FDA, EMA, and CDSCO inspectors.

Challenges

Key Challenges in Pharmaceuticals Laboratories

These are the operational, regulatory, and data-management pain points that labs in this industry face every day.

Maintaining 21 CFR Part 11 compliance with electronic signatures, audit trails, and data integrity (ALCOA+ principles)

Managing complex ICH stability study protocols across multiple storage conditions and time points

Automating OOS investigation workflows with root cause analysis and CAPA tracking

Handling high-volume QC testing with rapid batch release turnaround to meet production schedules

Integrating with HPLC, GC, dissolution, and other analytical instruments for direct data capture

Solutions

How LIMSera Solves Them

Purpose-built features that directly address the challenges your laboratory faces.

21 CFR Part 11 compliant electronic signatures with biometric and password-based authentication

ICH stability study planner with automated pull scheduling, storage condition monitoring, and trend analysis

OOS/OOT investigation workflow with configurable escalation paths and CAPA integration

Automated Certificate of Analysis (CoA) generation from approved test results

Instrument integration for HPLC, GC, UV-Vis, dissolution, and Karl Fischer systems

Batch genealogy and raw material traceability across the entire product lifecycle

Validated environment with IQ/OQ/PQ documentation package included

Parameters

Key Parameters Tested

Comprehensive parameter coverage for pharmaceuticals laboratory testing.

Assay and potency by HPLC, GC, UV-Vis, and titration methodsDissolution profiles (USP apparatus I–IV) across multiple time pointsRelated substances and impurity profiling (specified, unspecified, total)Microbial limits — TAMC, TYMC, absence of specified organisms (USP <61>/<62>)Water activity, moisture content (Karl Fischer), and loss on dryingParticle size distribution, bulk/tapped density, and flowabilityEndotoxin testing (LAL/rFC) and sterility testing for injectable products
Compliance

Compliance Standards

LIMSera helps you meet and maintain compliance with these regulatory and accreditation requirements.

21 CFR Part 11 — Electronic Records and Electronic Signatures
ICH Q2(R2) — Validation of Analytical Procedures
WHO GMP and Schedule M (India)
USP/EP/IP pharmacopoeial standards
EU Annex 11 — Computerised Systems
Case Study

A mid-size pharma manufacturer reduced batch release time from 5 days to 18 hours and eliminated three repeat FDA 483 observations related to data integrity after implementing LIMSera across their QC and stability departments.

See LIMSera in Action for Pharmaceuticals

Get a personalized walkthrough tailored to pharmaceuticals laboratory workflows, compliance needs, and integration requirements.